What's Happening

Mora N, Mehall M, Morlino R, Hopton T, Morrato E, Pincus H.

Lessons learned from sustaining and transitioning a national EHR data network: The ENACT experience applying D&I science frameworks. AcademyHealth 18th Annual Dissemination and Implementation Conference; December 16, 2025; National Harbor, MD. Poster presentation.

Mora N, Mehall M, Morrato E.

Sustaining electronic health record research networks in academic medical research centers: Insights from implementation science. 2025 Fall CTSA Program Annual Meeting; October 23, 2025. Poster presentation.

Wang Y, Hilsman J, Li C, Morris M, Heider PM, Fu S, Kwak MJ, Wen A, Applegate JR, Wang L.

Development and Validation of Natural Language Processing Algorithms in the National ENACT Network. Journal of Clinical and Translational Science. 2025:29-Jan.

This session brings together three leaders who have turned ENACT's federated EHR infrastructure into funded, published, real-world impact. Yanshan Wang (University of Pittsburgh), NLP Lead for the ENACT Network and PI on multiple NIH- and CTSI-funded AI projects, Sunyang Fu (UT Austin Dell Medical School), a leader of an ENACT NLP Subgroup, and Griffin Weber (Harvard Medical School / BIDMC), co-creator of the i2b2 and SHRINE platforms that underpin ENACT, will reflect on how the network's shared architecture has enabled grant-winning, multi-site collaborations across the CTSA consortium.

In this talk, Dr. Bell will present the Clinical Concierge Evidence Service which uses real-world data to provide clinicians with information to aid their clinical decision-making process with patients. He will discuss the need for this kind of service as well as the challenges to providing this kind of data to clinicians. Focusing on how ENACT has enabled the creation of this service, Dr. Bell will review how this service was developed, current challenges, and next steps including embedding AI with human in the loop oversite to improve timeliness of this service.

This talk will examine the research value of aggregated counts derived from the ENACT network. For instance, counts obtained via SHRINE can be beneficial for epidemiological research, pharmacovigilance, and the generation of clinical evidence. The presentation will discuss the strengths and limitations of count-based analyses and explore how to automate the execution of a large number of queries in SHRINE.