The Largest Federated Network for Regulatory-Compliant EHR-Based Research

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Active, reconnecting, and inactive nodes on the map of the ENACT network within the contiguous U.S.

ENACT enables…

Regulatory-Compliant EHR-Based Research

Improved data quality

Access to trainees for educational purposes

AI and machine learning analysis to large-scale EHR data sets

Informatics experts to develop and validate new tools

Clinical Decision Support

Current Capabilities of ENACT

The ENACT Network allows researchers to explore and validate feasibility for clinical studies from their desktops, providing a real-time platform for this purpose within the CTSA consortium.

It is equipped to assist researchers in designing and completing clinical studies, ensuring that the data and processes are secure and compliant with relevant regulations such as HIPAA.

Researchers can use the network to query patient data from participating sites, which includes demographics, diagnoses, lab results, and medications prescribed. This is to help determine the availability of suitable candidates for clinical studies.

Clip art of three people in business attire holding up cogs together.
Clip art of four people sitting/standing around an oversized tablet display discussing an overview.

ENACT History/Overview

The ENACT Network is OMOP compatible! Read below for more high level insights on our platform. Details can be found under the Technical Resources page.

ACT Ontology Updates: The network utilizes the ACT Ontology, which in version 4.2 includes updated UMLS, lab, demographics, SDOH, research, and vaccine ontologies.

SHRINE Upgrade: The Shared Health Research Information Network (SHRINE) is currently version 4.4.0, which enables configurable obfuscation to +/-3 and provides various query options not available in previous versions.

i2b2 Versions: The network has incorporated the i2b2 software for data management and research facilitation. Note that the i2b2 software is compatible with OMOP and i2b2 databases. The network is currently on version 1.8.2, although 1.8.1a is also acceptable.

These software elements reflect the ENACT Network’s commitment to maintaining a robust, up-to-date technical infrastructure to support clinical research and data analysis.